Diabetic circulatory insufficiency is a condition where high blood glucose levels cause fatty deposits to form inside blood vessels, reducing blood flow, especially to the feet. This can impair oxygen and nutrient delivery, impede wound healing, and increase the risk of infection. Current treatments include angioplasty or bypass surgery which are costly, ineffective and require administration by a healthcare professional. Poor circulation can lead to diabetic foot ulcers, particularly on the lower extremities. These ulcers are formed as a result of skin tissue breaking down, often accompanied by infection at the site of pressure. If left untreated, these ulcers can lead to more serious complications, including the need for amputation.

• 20% of diabetic hospital admissions are patients experiencing a foot ulcer caused by DCI

•  5 year mortality rate following first time ulceration is approximately 40%

•  DFU precedes  >85% of major amputations in patients with diabetes

• 1 in 4 diabetics develop a Diabetic Foot Ulcer as a result of DCI